Sf. Egger et al., BACTERIAL-CONTAMINATION DURING EXTRACAPSULAR CATARACT-EXTRACTION - PROSPECTIVE-STUDY ON 200 CONSECUTIVE PATIENTS, Ophthalmologica, 208(2), 1994, pp. 77-81
Postoperative endophthalmitis remains one of the most devastating comp
lications of eye surgery. In recent years infections with so called 'n
onpathogenic' organisms like Propionibncterium acnes or coagulase-nega
tive staphylococci have gained in importance. 200 patients were includ
ed in this study, from whom preoperative smears of the conjunctiva and
intraoperative aspirates of the anterior chamber (at the start and at
the end of the operation) had been taken. All samples were investigat
ed for aerobe and anaerobe microorganisms and fungi. 75% of the preope
rative smears had been contaminated, with coagulase-negative staphyloc
occi the most commonly isolated bacteria. But, in addition, 28% of the
patients had culture-positive anterior chamber aspirates, also with c
oagulase-negative staphylococci as the most frequent organisms. In all
cases inoculum sizes were extremly small (10-20 c.f.u./ml). Probably
because of this small inoculum, but also due to the bacteriocidal qual
ities of the acqueous humor and the integrity of the posterior capsule
sac, in no case had postoperative endophthalmitis developed. For the
first time, our study tried to correlate the contamination of the ante
rior chamber aspirate to the used operation technique: first results s
how that the contamination of the aqueous humor is significantly lower
(p < 0.03) if the cataract extraction is performed by phacoemulsifica
tion than if done without.