A NEW SYSTEM FOR RECORDING ELECTRORETINOGRAPHICAL POTENTIALS IN ANIMALS

Electroretinography can provide meaningful evidence of oculotoxic chan ges. We describe a new recording system specially constructed for anim al experiments. It meets the standards for electroretinographical inve stigations and recording systems set up by international committees. T he recording apparatus has a resolution of 0.49 mu V (amplitude) and 1 ms with a sensitivity range of +/-1 mV full scale and a band-pass of 0.03 to 1,000 Hz. The signals are digitized and processed by a compute r. The calibration symbol is faithfully represented as a rectangular i mpulse with an amplitude of 100 mu V and a period of 100 ms. Normal va lues were calculated for 25-week-old albino Wistar rats. The normal ra nge is defined as the mean +/-2 SD for A and B wave parameters. These normal values can serve as reference values for future studies in ocul otoxicity.