AUTISM IN THALIDOMIDE EMBRYOPATHY - A POPULATION STUDY

Authors
STROMLAND K NORDIN V MILLER M AKERSTROM B GILLBERG C
Citation
K. Stromland et al., AUTISM IN THALIDOMIDE EMBRYOPATHY - A POPULATION STUDY, Developmental Medicine and Child Neurology, 36(4), 1994, pp. 351-356
Citations number
19
Categorie Soggetti
Pediatrics,"Clinical Neurology
Journal title
Developmental Medicine and Child Neurology → ACNP
ISSN journal
00121622
Volume
36
Issue
4
Year of publication
1994
Pages
351 - 356
Database
ISI
SICI code
0012-1622(1994)36:4<351:AITE-A>2.0.ZU;2-C
Abstract
Of a population of 100 Swedish thalidomide embryopathy cases, at least four met full criteria for DSM-III-R autistic disorder and ICD-10 chi ldhood autism. Thalidomide embryopathy of the kind encountered in thes e cases affects fetal development early in pregnancy, probably on days 20 to 24 after conception. It is argued that the possible association of thalidomide embryopathy with autism may shed some light on the iss ue of which neural circuitries may be involved in autism pathogenesis.