CLONING OF A CDNA-ENCODING OVINE INTERLEUKIN-3

Authors
MCINNES CJ LOGAN M HAIG D WRIGHT F
Citation
Cj. Mcinnes et al., CLONING OF A CDNA-ENCODING OVINE INTERLEUKIN-3, Gene, 139(2), 1994, pp. 289-290
Citations number
11
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
139
Issue
2
Year of publication
1994
Pages
289 - 290
Database
ISI
SICI code
0378-1119(1994)139:2<289:COACOI>2.0.ZU;2-T
Abstract
A cDNA encoding the ovine hematopoietic growth factor interleukin-3 (I L-3), has been cloned. A 560-bp cDNA, containing the entire protein co ding region, was amplified from activated mesenteric lymph node cells. The cDNA was found to share 58% nucleotide identity with hIL-3 and 48 % identity with mIL-3. The predicted ovine amino-acid sequence shares 36 and 30% identity, respectively, with the corresponding human and mu rine proteins.