Objective: Although MR has been proven effective in evaluating many co
mponents of the musculoskeletal system, including ligaments, fibrocart
ilage, muscle, and bone marrow, its role in the evaluation of articula
r cartilage remains controversial. Recent studies have demonstrated th
at intraarticular injection of Gd-DTPA [MR arthrography (MRA)] improve
s the detection of cartilage abnormalities in cadaveric specimens. The
aim of this study was to determine the efficacy of MRA for the detect
ion of naturally occurring cartilage lesions in a clinical population.
Materials and Methods: Sixty knees of 58 patients were studied with a
three-dimensional (3D) T2-weighted GE sequence (FISP) both before an
d after and a T1-weighted (T1W) SE sequence after the intraarticular i
njection of a 2 mmol/L Gd-DTPA solution. All knees subsequently underw
ent arthroscopy or arthrotomy. Results: The MRA sequences performed si
gnificantly better(K = 0.85) than the routine FISP sequences (K = 0.39
) in both the detection and the staging of cartilage abnormalities. Th
e MRA FISP sequence (K = 0.91) performed slightly better than the MRA
T1W sequence (K = 0.85), but there was no statistically significant di
fference between the two sequences. No complications from the intraart
icular injection of contrast material occurred. Conclusion: Therefore,
MRA appears to be an effective and safe method for the evaluation of
articular cartilage abnormalities.