Mr. Sposto et al., PARACOCCIDIOIDOMYCOSIS MANIFESTING AS ORAL LESIONS - CLINICAL, CYTOLOGICAL AND SEROLOGICAL INVESTIGATION, Journal of oral pathology & medicine, 23(2), 1994, pp. 85-87
Paracoccidioidomycosis (South American blastomycosis) is a systemic my
cosis which can be associated with oral lesions. This study on a group
of 14 patients showed oral lesions mainly on the gingival or alveolar
mucosa, with pulmonary involvement detectable on chest radiography in
most. Microscopic detection of the fungus on a direct smear showed po
sitive results in all 14 patients. Serological investigations includin
g immunodiffusion, counterimmunoelectrophoresis and immunoblot were al
so positive in 100% of cases. The results suggest that direct smear to
gether with serology may obviate the need for lesional biopsy for the
diagnosis of oral paracoccidioidomycosis.