NOVEL JUVENOIDS OF THE 2-(4-HYDROXYBENZYL)CYCLOHEXAN-1-ONE SERIES

A series of insect juvenile hormone analogs (juvenoids) was synthesize d and studied. The basic skeleton of these juvenoids contains three ri ngs and a short aliphatic subunit and bears two or three chiral center s (depending on the appropriate structure; see 6-9). The chiral center located in the 1,2-diphenoxypropane subunit has the configuration (RS ), (R) (a series), or (S) (b series). The juvenoids were subjected to a biological screening, the preliminary results of which are briefly d escribed.