The H2O megamaser in IC 10SE has been observed at roughly monthly inte
rvals using the Haystack Observatory from 1986 until 1993 as part of a
monitoring program of galaxies with strong water masers. The IC 10SE
maser features show strong variability in line strength, line velocity
, and line width. An outburst of a single feature at -324 km s-1 with
a flux density increase of 400 lasts for about 1 year. The characteris
tics of the features support unsaturated masering and amplification of
background radio continuum.