Purpose: A modified Jones test is used to assess whether lacrimal tran
sit time varies with age. Methods: The right eyes of 101 control subje
cts and 18 patients suspected of having lacrimal system abnormalities
were tested with one drop of 2% sodium fluorescein solution. A cotton
applicator was placed in the nose next to the inferior turbinate and p
articipants were asked to lean forward. Dye passage was assessed every
3 minutes for 24 minutes. Results: The results were assessed by age.
In control subjects, there seemed to be a natural break in the distrib
ution of the data at the age of 45 to 50 years. In control subjects yo
unger than 45 years of age, 10/11 (91%) passed dye in 6 minutes or les
s (median = 3 minutes), whereas in those 45 years of age and older, 79
/90 (84%) passed dye in 12 minutes or less (median = 6 minutes). The r
esults were statistically significant (P = 0.0091). In contrast, patie
nts with symptoms of epiphora due to a nasolacrimal duct obstruction h
ad lacrimal transit times in excess of the above limits. Conclusion: T
his study confirms that the lacrimal transit time slows with age. The
modification of the Jones test presented here requires a cutoff of 6 m
inutes in patients younger than 45 years of age and 12 minutes in pati
ents 45 years of age and older.