ENCAPSULATED CELLS FOR SUSTAINED NEUROTRANSMITTER DELIVERY TO THE CENTRAL-NERVOUS-SYSTEM

Authors
Citation
Pa. Tresco, ENCAPSULATED CELLS FOR SUSTAINED NEUROTRANSMITTER DELIVERY TO THE CENTRAL-NERVOUS-SYSTEM, Journal of controlled release, 28(1-3), 1994, pp. 253-258
Citations number
21
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
ISSN journal
01683659
Volume
28
Issue
1-3
Year of publication
1994
Pages
253 - 258
Database
ISI
SICI code
0168-3659(1994)28:1-3<253:ECFSND>2.0.ZU;2-V
Abstract
Recent studies evaluating the therapeutic usefulness of an implantable , bioartificial prosthesis for treating Central Nervous System (CNS) d isorders are reviewed. A description of the implant along with advanta ges over conventional technology is presented. Experimental evidence f rom in vitro and in vivo experiments suggests the potential usefulness of this approach in the treatment of such CNS disorders as Parkinson' s disease and chronic pain that may be treated by the sustained releas e of one or more neuroactive agents in a specific location.