Human papillomavirus is a common sexually transmitted infection associ
ated with cervical dysplasia. We investigated the extent of urethral h
uman papillomavirus infection by performing urethrocystoscopy on 90 me
n who presented to a sexually transmitted disease clinic with external
meatal warts. A total of 83 men underwent biopsies and in 49 human pa
pillomavirus typing was done. Of 90 men with external meatal warts 75
(83.3%) had no other warts, while 15 (16.7%) also had more proximal le
sions. Only 5 men (5.6%) had lesions at or beyond the pendulous urethr
a. Of the 90 men 12 (13.3%) had 2 warts, 3 (3.3%) had 3 warts and none
had more than 3 warts. A total of 39 men had human papillomavirus typ
e 6/11, 1 had type 31/33/35 and 9 were negative for human papillomavir
us antigens. Histological evaluation of biopsies showed no dysplasia.
Our study confirms that the frequency of internal urethral warts is lo
w. Human papillomavirus infection was not associated with urethral dys
plasia.