METASTATIC TESTICULAR CHORIOCARCINOMA AND SECONDARY HYPERTHYROIDISM -CASE-REPORT AND REVIEW OF THE LITERATURE

We report on a 16-year-old boy with metastatic testicular choriocarcin oma, increased levels of human chorionic gonadotropin and profound hyp erthyroidism bordering on thyroid storm. Hyperthyroidism was secondary to elevated human chorionic gonadotropin, with a thyroid-stimulating hormone effect. Management consisted of suppressive therapy for the sy mptoms of thyrotoxicosis until chemotherapy achieved control of the pr imary tumor and elevated levels of human chorionic gonadotropin. Revie w of the urological literature demonstrated a lack of recognition of t his potentially serious paraneoplastic syndrome and its management.