Medroxyprogesterone acetate (Depo-Provera) is now approved for use as
an injectable contraceptive. It is highly effective and has the advant
age of only needing to be administered once every 12 weeks. The most c
ommon side effects are menstrual irregularities, amenorrhea in particu
lar. Several illustrative cases are presented that demonstrate appropr
iate patient selection for this agent.