DESIGN, STRUCTURE-ACTIVITY AND X-RAY CRYSTALLOGRAPHIC STUDIES OF PSEUDO-SYMMETRICAL NONPEPTIDYL HIV-1 PROTEASE INHIBITORS

Authors
BABINE RE ZHANG N SCHOW SR XU ZB BYRN RA HASTINGS RC SEMMELHACK MF WICK MM KERWAR SS
Citation
Re. Babine et al., DESIGN, STRUCTURE-ACTIVITY AND X-RAY CRYSTALLOGRAPHIC STUDIES OF PSEUDO-SYMMETRICAL NONPEPTIDYL HIV-1 PROTEASE INHIBITORS, Bioorganic & medicinal chemistry letters, 4(4), 1994, pp. 583-588
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
4
Issue
4
Year of publication
1994
Pages
583 - 588
Database
ISI
SICI code
0960-894X(1994)4:4<583:DSAXCS>2.0.ZU;2-Z
Abstract
A new class of nonamino acid derived HIV-1 protease inhibitors of stru cture 1 are described. Structure activity relationships are discussed in the context of a protein crystal complex.