EFFECT OF THEOPHYLLINE ON ADAPTATION OF THE HEART TO MYOCARDIAL-ISCHEMIA DURING PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY IN PATIENTS WITH STABLE ANGINA-PECTORIS

Authors
HASHIMURA K KIJIMA Y MATSUURA Y UEDA T KATO Y MORI I MINAMINO T KITAKAZE M HORI M
Citation
K. Hashimura et al., EFFECT OF THEOPHYLLINE ON ADAPTATION OF THE HEART TO MYOCARDIAL-ISCHEMIA DURING PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY IN PATIENTS WITH STABLE ANGINA-PECTORIS, The American journal of cardiology, 79(4), 1997, pp. 475
Citations number
17
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
The American journal of cardiology → ACNP
ISSN journal
00029149
Volume
79
Issue
4
Year of publication
1997
Database
ISI
SICI code
0002-9149(1997)79:4<475:EOTOAO>2.0.ZU;2-Q
Abstract
This study was designed to examine whether theophylline, an adenosine receptor antagonist, affects cardiac adaptation to ischemia during pro gression of repetitive balloon inflations of percutaneous transluminal coronary angioplasty (PTCA). Theophylline abolished this cardiac adap tation, suggesting that endogenous adenosine is a key mediator for car diac adaptation during PTCA.