Pheromone production and/or release by beetles is coordinated with a v
ariety of behavioral, physiological, and environmental factors. To dat
e, two basic mechanisms for the regulation of pheromone biosynthesis i
n beetles have been proposed. Pheromone biosynthesis may simply be dep
endent on the availability of biosynthetic precursors. Alternatively,
certain stimuli or events may trigger pheromone biosynthesis via juven
ile hormone (JH) action. JH may either act directly at the site of phe
romone biosynthesis to enhance pheromone production or may act indirec
tly, through a brain hormone (which might be related to the pheromone
biosynthesis activating neuropeptide) or through effects on antennal s
ensory response. Knowledge of the regulation of the initiation and ter
mination of pheromone biosynthesis is reviewed. Mechanisms by wh ich p
heromone stereochemistry is controlled are also discussed. This is an
important aspect of pheromone production in Coleoptera, since slight c
hanges in the stereochemistry can completely alter the activity of the
molecule. (C) 1994 Wiley-Liss, Inc.