Jy. Sanceau et al., LIGNANS .17. RESEARCH PERTAINING TO THE T OTAL SYNTHESIS OF A NORCYCLONEOLIGNAN, METASEQUIRIN-B, Tetrahedron, 50(11), 1994, pp. 3363-3380
The total synthesis of the racemic furano bisbenzocycloheptene 3 is de
scribed. The compound 3, which contains five asymmetric centres, is th
e 5,8-bis-epimer of the tetra-O-methyl derivative of metasequirin-B (1
), a norcycloneolignan of unusual structure.