A PRACTICAL SYNTHETIC METHOD FOR ENANTIOENRICHED ALPHA-HYDROXYSTANNANES

Authors
TOMOOKA K IGARASHI T NAKAI T
Citation
K. Tomooka et al., A PRACTICAL SYNTHETIC METHOD FOR ENANTIOENRICHED ALPHA-HYDROXYSTANNANES, Tetrahedron letters, 35(12), 1994, pp. 1913-1916
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
12
Year of publication
1994
Pages
1913 - 1916
Database
ISI
SICI code
0040-4039(1994)35:12<1913:APSMFE>2.0.ZU;2-1
Abstract
The TiCl4-promoted reaction of (4S, 6S)-(4,6-dimethyl-1,3 -dioxan-2-yl )-tributylstannane with Grignard reagents is shown to afford, after ox idation followed by base treatment, the (S)-alpha-hydroxystannanes in >95 similar to 20% ee.