An ileitis developing years or months after ileostomy was recognised a
nd described many years ago but has rarely been mentioned since. We de
scribe nine patients with a non-specific preanastomotic ileitis that d
eveloped years after colectomy in patients operated on for ulcerative
colitis or carcinoma. The disease developed after various types of rec
onstruction: ileorectal, ileoanal, with or without pouch. The diseased
ileum showed inflammation, erosions, ulcerations, and sometimes stric
tures. The disease course ranged from asymptomatic to severe pain and
diarrhoea. No specific cause could be shown. Granulomas, infectious ag
ents or ischaemic changes were not found. The anastomosis was always p
atent. Three patients have had numerous episodes of intestinal obstruc
tion presumably because of adhesions. Seven of nine patients were fema
le. The response to steroids, 5-aminosalicyclic acid preparations, and
methotrexate was poor, three patients responded well to azathioprine.
The condition is not rare and the cause remains unknown.