N. Soehendra et al., PULVERIZATION OF CALCIFIED AND NON-CALCIFIED GALL-BLADDER STONES - EXTRACORPOREAL SHOCK-WAVE LITHOTRIPSY USED ALONE, Gut, 35(3), 1994, pp. 417-422
Using a modified electromagnetic lithotripter (Siemens), extracorporea
l shock wave lithotripsy (ESWL) was performed in 260 patients with gal
l bladder stones. Exclusion criteria for treatment were a non-function
ing gall bladder, subcostal gall bladder location, and multiple stones
occupying more than three quarters of the gall bladder volume. Stone
pulverisation was the end point of ESWL. The number of shock wave disc
harges and sessions was not limited. Pulverisation was achieved in 250
patients (96.1%) after a median of three ESWL sessions (range 1-21).
The number of sessions required depended upon stone composition and bu
rden. More than three sessions were required in 60.2% of patients with
calcified stones compared with 35.9% of patients with non-calcified s
tones (p<0.001). 65.8% of patients with stones measuring more than 30
mm in total diameter required more than three sessions compared with 4
2.9% of patients with a stone burden less than 30 mm (p<0.01). At 18-2
4 (8-12) months follow up, stone clearance was achieved in 94.3% (80.4
%) of patients with non-calcified stones, compared with 89.5% (76.8%)
in patients with calcified stones and in 75% (71.4%) of patients with
a total stone diameter more than 30 mm compared with 95.7% (80.4%) for
patients with a total stone diameter less than 30 mm (p<0.05). ESWL r
elated complications (gross haematuria) occurred in three patients. Th
irty six (13.8%) patients experienced biliary colic; four had cholecys
tectomy, and five endoscopic papillotomy because of common bile duct o
bstruction. Stone recurrence was seen in 5.3% of patients over a follo
w up period of up to two years (median 16.6 months).