COMPARISON OF ASSAY-METHODS BY 2ND-DERIVATIVE SPECTROSCOPY, COLORIMETRY AND FLUORESCENCE SPECTROSCOPY OF SALICYLIC-ACID IN ASPIRIN PREPARATIONS WITH A HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD

Authors
TORRADO S TORRADO S CADORNIGA R
Citation
S. Torrado et al., COMPARISON OF ASSAY-METHODS BY 2ND-DERIVATIVE SPECTROSCOPY, COLORIMETRY AND FLUORESCENCE SPECTROSCOPY OF SALICYLIC-ACID IN ASPIRIN PREPARATIONS WITH A HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD, Journal of pharmaceutical and biomedical analysis, 12(3), 1994, pp. 383-387
Citations number
19
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Journal of pharmaceutical and biomedical analysis → ACNP
ISSN journal
07317085
Volume
12
Issue
3
Year of publication
1994
Pages
383 - 387
Database
ISI
SICI code
0731-7085(1994)12:3<383:COAB2S>2.0.ZU;2-L
Abstract
Second-derivative spectroscopy, colorimetry and fluorescence spectrosc opy have been compared with a high-performance liquid chromatographic (HPLC) method for the assay of salicylic acid in preparations of aspir in. Results are presented for the linearity, sensitivity and reproduci bility of these methods. The second-derivative spectroscopic and the H PLC methods were acceptable in terms of linearity, sensitivity and int er-day reproducibility and were convenient for the routine analysis of salicylic acid in aspirin preparations.