P. Spegelaere et al., LACK OF A DETECTABLE EFFECT OF CAPSID PROTEINS ON THE CELL-DEPENDENT ACTIVITY OF PARVOVIRUS MVMP PROMOTERS, Research in virology, 145(1), 1994, pp. 5-12
Deletion of upstream elements from the early P4 promoter of parvovirus
MVM (minute virus of mice, prototype strain MVMp) has a differential
effect on its activity, depending on the host cell considered. This in
dicates that upstream motifs participate in the control of promoter P4
functioning and are responsive to factors which are, at least in part
, cell-type specific. In contrast with other viral systems, the capsid
proteins of MVMp had no detectable effect on gene expression driven b
y either the early P4 or late P38 promoter of MVMp in permissive and n
on-permissive cells.