We report here on our experience of clinically relevant bleeding after
endoscopic sphincterotomy (ES). Relevant bleeding was defined by the
occurrence of (a) hematemesis or melena and (b) at least a two-point d
rop in hemoglobin, with no other bleeding source on endoscopy. These t
wo criteria were met in 16 patients between 1983 and 1992. They repres
ented 0.65 % of all ES procedures performed during this period. Bleedi
ng occurred immediately after ES in five cases, and was delayed in 11
cases from one to eight days (mean two days). Patients were retrospect
ively classified into three groups according to the severity of bleedi
ng and subsequent clinical management. In six cases (group 1), bleedin
g developed slowly without shock and stopped spontaneously. In five ca
ses (group 2), bleeding developed rapidly with melena and a drop in he
moglobin, but without shock. These patients were successfully managed
with sclerotherapy without any further complications. The five patient
s in Group 3 had brisk bleeding with hematemesis and shock. Endoscopic
hemostasis could not be performed; emergency arteriography disclosed
active bleeding in four patients, and embolization of the gastroduoden
al artery was performed. Bleeding stopped in all patients. Billroth II
anastomosis appeared to be the only factor associated with an increas
ed risk of clinically relevant bleeding. It was possible to control bl
eeding following ES using endoscopic or angiographic hemostasis, surge
ry being avoided in all cases.