THE APPLICATION OF EPR SPECTROSCOPY IN THE FIELD OF PHARMACY

The purpose of this paper is to provide an overview of applications of electron paramagnetic resonance spectroscopy in pharmacy and medicine in order to facilitate its increased use. Applications include the ch aracterization of systems containing endogenous paramagnetic materials . By means of spin labeling techniques it is possible to determine mic roviscosity, micropolarity, sulfhydryl groups, pH-values and partial p ressure of oxygen. Pharmaceutical aspects of EPR imaging as well as in vivo EPR are discussed.