PREGNANCY AND MULTIPLE-SCLEROSIS - THE INFLUENCE ON LONG-TERM DISABILITY

Citation
P. Verdru et al., PREGNANCY AND MULTIPLE-SCLEROSIS - THE INFLUENCE ON LONG-TERM DISABILITY, Clinical neurology and neurosurgery, 96(1), 1994, pp. 38-41
Citations number
13
Categorie Soggetti
Neurosciences,Surgery
ISSN journal
03038467
Volume
96
Issue
1
Year of publication
1994
Pages
38 - 41
Database
ISI
SICI code
0303-8467(1994)96:1<38:PAM-TI>2.0.ZU;2-M
Abstract
We studied 200 female patients with multiple sclerosis (MS) to investi gate whether pregnancy after the onset of disease influences long term disability. As an index of progression, we used the time between dise ase onset and wheel-chair dependence. Patients who had at least one pr egnancy after onset were wheelchair dependent after 18.6 years, versus 12.5 years for the other women (P < 0.0001). This difference remains statistically significant after correction for age at onset of disease .