HLA-DR POSITIVE EPIDERMAL LANGERHANS CELLS IN LIVER-CIRRHOSIS AND IMMUNOSUPPRESSED LIVER TRANSPLANTED PATIENTS

Authors
GILHAR A ENAT R BARUCH Y
Citation
A. Gilhar et al., HLA-DR POSITIVE EPIDERMAL LANGERHANS CELLS IN LIVER-CIRRHOSIS AND IMMUNOSUPPRESSED LIVER TRANSPLANTED PATIENTS, Acta dermato-venereologica, 74(2), 1994, pp. 93-94
Citations number
11
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
Acta dermato-venereologica → ACNP
ISSN journal
00015555
Volume
74
Issue
2
Year of publication
1994
Pages
93 - 94
Database
ISI
SICI code
0001-5555(1994)74:2<93:HPELCI>2.0.ZU;2-M
Abstract
The aim of the present study was to evaluate the number of Langerhans' cells (LC) in immunosuppressed liver transplanted patients, compared to patients with liver cirrhosis and healthy volunteers. The detection of I.C was performed in the epidermal sheet of each patient by using indirect immunoperoxidase and ATPase staining. A significant reduction in the number of LC was found in the liver transplanted patients as c ompared to patients with liver cirrhosis and healthy volunteers. This reduction may be related to prolonged treatment with corticosteroids a nd azathioprine.