IG-A ANTIBODIES TO KLEBSIELLA IN ANKYLOSING-SPONDYLITIS

Citation
O. Ardicoglu et al., IG-A ANTIBODIES TO KLEBSIELLA IN ANKYLOSING-SPONDYLITIS, Clinical rheumatology, 15(6), 1996, pp. 573-576
Citations number
25
Categorie Soggetti
Rheumatology
Journal title
ISSN journal
07703198
Volume
15
Issue
6
Year of publication
1996
Pages
573 - 576
Database
ISI
SICI code
0770-3198(1996)15:6<573:IATKIA>2.0.ZU;2-5
Abstract
In this study anti-klebsiella Ig A values were compared in 40 patients with definite diagnosis of ankylosing spondylitis and a control group of 40 healthy subjects, Anti-Klebsiella Ig A antibody values were sig nificantly higher in patients with ankylosing spondylitis as compared to the control group (p < 0.001), Correlation between these antibodies and erythrocyte sedimentation rate, CRP, serum Ig A, HLA B 27, age, s ex and disease duration was searched, but no correlation was found, In our opinion, these results support the suggestion that inflammatory r esponse in ankylosing spondylitis is triggered by Klebsiella but is in sufficient to prove the causal relationship between ankylosing spondyl itis and Klebsiella.