Evaluating joint involvement in rheumatoid arthritis in a key clinical
assessment, We investigated the extent of variation in measurement of
joint swelling and tenderness and evaluated the impact of training to
standardise methods, Eight observers (medical and nursing staff) exam
ined eight rheumatoid patients for joint swelling and tenderness befor
e and after training in clinical methods, The EULAR handbook for joint
evaluation was used for training and assessments were based on the 28
joint count, There was extensive variability in both numbers of swoll
en and tender joints, Coefficients of variation for articular indices
recorded by the 8 observers in individual patients were often high (up
to a maximum of 204%), indicating considerable differences between ob
servers, Training had an impact on the assessment of the numbers of sw
ollen joints which increased by a mean of 32% (P < 0.05) and the numbe
r of tender joints which increased by 41% (p < 0.01), Training had onl
y a limited impact on the variation among observers in determining the
number of swollen and number of tender joints, After training, the me
an coefficients of variation were still 59% for swollen joints and 65%
for tender joints, These results highlight the extent of variation in
clinical assessment of rheumatoid arthritis and show the advantages o
f training, It leads to increased sensitivity of measurement, Standard
isation appears essential for clinical studies.