X-RAY DETERMINED MOLECULAR-STRUCTURE OF PHA-H,10-ALPHA-H,11-ALPHA-H-GUAI-3,4-EN-6,12-OLIDE (CLADANTHOLIDE)

Authors
KRAJEWSKI JW GLUZINSKI P DANIEWSKI WM GUMULKA M KEMME A MISHNEV A
Citation
Jw. Krajewski et al., X-RAY DETERMINED MOLECULAR-STRUCTURE OF PHA-H,10-ALPHA-H,11-ALPHA-H-GUAI-3,4-EN-6,12-OLIDE (CLADANTHOLIDE), Polish Journal of Chemistry, 68(3), 1994, pp. 509-513
Citations number
8
Categorie Soggetti
Chemistry
Journal title
Polish Journal of Chemistry → ACNP
ISSN journal
01375083
Volume
68
Issue
3
Year of publication
1994
Pages
509 - 513
Database
ISI
SICI code
0137-5083(1994)68:3<509:XDMOP>2.0.ZU;2-S
Abstract
The compound H,7alphaH,10alphaH,11alphaH-guai-3,4-en-6,12-olide (Clada ntholide) (1) has been isolated and its structure investigated by X-ra y diffraction. The compound crystallizes in an orthorhombic system, sp ace group P2(1)2(1)2(1), Z = 4, a = 7.961(2), b = 11.598(5), c = 14.45 1(4) angstrom. The structure was solved by direct methods and refined by a full-matrix, least-squares procedure to give R = 0.0507 and R(ome ga) = 0.0338, (omega = 0.957/sigma(F)2). The stereochemistry of 1 as p ostulated from earlier spectromolecular investigations was fully confi rmed.