IMPACT OF DIETARY YOGURT ON IMMUNE FUNCTION

Studies of the effects of yogurt on immunity and atopic diseases have suggested improvements in cytokine (interleukin-2 and interferon-gamma ) responses and clinical scores in patients with allergic rhinitis. Th is study compares prospectively immune parameters of participants who received 16 oz of yogurt versus 16 oz of milk/day in a randomized cros s-over design. Yogurt that contained live, active Lactobacillus bulgar icus and Streptococcus thermophilus or 2% milk was consumed for one mo nth each, Twenty otherwise healthy adults with atopic histories docume nted by skin testing were enrolled. Immune studies were performed at t he beginning and end of the two 1-month study phases, separated by a a -week washout period. These studies included measurements of cellular humoral, and phagocytic function. No adverse events were noted in eith er group. No significant improvements in any immune parameter were not ed, The consumption of yogurt that contained the live active bacteria L bulgaricus and S thermophilus does not appear to enhance immune func tion in atopic individuals at the dosage and duration used in this stu dy.