DIFFERENTIAL-EFFECTS OF LESIONS OF THE DORSOMEDIAL AND DORSOLATERAL CAUDATE-PUTAMEN ON REACTION-TIME PERFORMANCE IN RATS

Authors
HAUBER W SCHMIDT WJ
Citation
W. Hauber et Wj. Schmidt, DIFFERENTIAL-EFFECTS OF LESIONS OF THE DORSOMEDIAL AND DORSOLATERAL CAUDATE-PUTAMEN ON REACTION-TIME PERFORMANCE IN RATS, Behavioural brain research, 60(2), 1994, pp. 211-215
Citations number
22
Categorie Soggetti
Neurosciences
Journal title
Behavioural brain research → ACNP
ISSN journal
01664328
Volume
60
Issue
2
Year of publication
1994
Pages
211 - 215
Database
ISI
SICI code
0166-4328(1994)60:2<211:DOLOTD>2.0.ZU;2-L
Abstract
In order to investigate the role of the dorsomedial and dorsolateral c audate-putamen (CPu) in movement initiation of rats, we examined the e ffects of quinolinic acid lesions (30 nmol in 1 mu l) in these striata l subregions in a simple reaction time task. Results show that lesions of the dorsomedial, but not of the dorsolateral CPu increased reactio n times. These findings provide further evidence for a functional hete rogenity of the CPu and demonstrate an involvement of the dorsomedial CPu in processes related to rapid initiation of responses.