STRESSOR PREDICTABILITY INFLUENCES OPEN-FIELD BEHAVIOR, PAIN SENSITIVITY AND BRAIN MAO INHIBITORY ACTIVITY (TRIBULIN) IN THE RAT

Authors
LEMOINE AP ARMANDO I BRUN JC BARONTINI M SEGURA ET
Citation
Ap. Lemoine et al., STRESSOR PREDICTABILITY INFLUENCES OPEN-FIELD BEHAVIOR, PAIN SENSITIVITY AND BRAIN MAO INHIBITORY ACTIVITY (TRIBULIN) IN THE RAT, Behavioural brain research, 61(1), 1994, pp. 91-95
Citations number
31
Categorie Soggetti
Neurosciences
Journal title
Behavioural brain research → ACNP
ISSN journal
01664328
Volume
61
Issue
1
Year of publication
1994
Pages
91 - 95
Database
ISI
SICI code
0166-4328(1994)61:1<91:SPIOBP>2.0.ZU;2-7
Abstract
The effects of predictable or unpredictable shocks on ambulation, pain sensitivity, plasma catecholamines and heart and brain monoamine oxid ase (MAO) inhibitory activity were investigated in rats. Animals showe d plasma catecholamines and heart MAO inhibitory activity sensitizatio n irrespective of type of treatment, while differences between groups were observed when open field and hot plate tests and brain MAO inhibi tory activity were considered. These effects parallel those observed u sing the classic triadic design leading to the helpless state. Our res ults suggest that predictability per se is able to generate this pheno menon.