Temporal lobectomy abolished complex partial seizures (CPSs) in 14 con
secutive children (12 years or younger) whose presurgical evaluation i
ncluded clinical analysis, scalp EEG, and neuroimaging. Seizures of 13
of 14 patients began with a simple partial component whose symptoms w
ere suggestive of limbic system involvement. EEG recorded clinically t
ypical seizures arising from the ultimately operated on temporal lobe
in seven (50%) and never falsely lateralized seizure origin. Most acti
ve interictal spikes arose from the epileptogenic temporal lobe in 13
(93%) and never falsely lateralized epileptogenesis. Neuroimaging disc
losed epileptogenic lesions in all: magnetic resonance imaging (MRI; 1
1 patients) and computed tomography (CT; three patients). Children may
obtain relief from CPSs by temporal lobectomy without invasive electr
oencephalography.