ANAPHYLACTOID PURPURA WITH INTESTINAL PERFORATION - REPORT OF A CASE AND REVIEW OF THE JAPANESE LITERATURE

A 78 year old man suffering from anaphylactoid purpura complained of a bdominal pain and bloody stools. Combined therapy with Prednisolone an d cyclophosphamide had been given against nephrotic syndrome caused by purpura nephritis. Severe abdominal pain with symptoms and signs of p anperitonitis necessitated laparotomy. Rectosigmoid perforation due to necrotizing angiitis (phlebitis) was also demonstrated histologically . The patient died of septicemia 18 days after surgery. Perforation of the alimentary tract rarely occurs in anaphylactoid purpura. Twenty s imilar cases were briefly reviewed from the Japanese literature.