La. Nicholson et al., PHYLOGENETIC RELATIONSHIP OF FUSOBACTERIUM-NECROPHORUM A-BIOTYPE, AB-BIOTYPE, AND B-BIOTYPE BASED UPON 16S RIBOSOMAL-RNA GENE SEQUENCE-ANALYSIS, International journal of systematic bacteriology, 44(2), 1994, pp. 315-319
The 16S rRNA genes from virulent (AB) and benign (B) biotype strains o
f Fasobacterium necrophorum, the causative agent of ovine foot abscess
, were cloned and sequenced. Notwithstanding the distinct phenotypic d
ifferences between the AB and B biotypes, a phytogenetic analysis in w
hich the 168 rRNA gene sequences were used revealed the close relation
ship of these taxa. Comparison df the virulent and benign biotypes of
F. necrophorum may therefore be a legitimate way to identify key virul
ence factors useful in vaccine development.