FINE-NEEDLE ASPIRATION DIAGNOSIS OF ANGIOMYOLIPOMA OF THE LIVER USINGA CELL BLOCK WITH IMMUNOHISTOCHEMICAL STUDY - A CASE-REPORT

Fine needle aspiration diagnosis of hepatic angiomyolipoma has been re ported rarely. Below we report one such case diagnosed by examination of a cell block. The pres ence of epithelioid smooth muscle cells, mat ure adipocytes, thick-walled vessels and extramedullary hematopoiesis established the diagnosis. It was further substantiated by positive st aining of the epithelioid cells for muscle-specific actin (HHF-35). Th e epithelioid cells were also immunoreactive with a melanocytic marker , HMB-45, but not with desmin, vimentin, cytokeratin or S-100 protein. HMB-45 might prove to be a sensitive marker for the epithelioid smoot h muscle component of the tumor. The advantage of the routine use of a cell block in fine needle aspiration is emphasized.