The precise roles of fiberoptic bronchoscopy (FOB) and computed tomogr
aphy (CT) of the chest in the evaluation of patients presenting with h
emoptysis have not been clearly defined, On the assumption that both p
rocedures would likely provide unique and complementary information, a
prospective study with blinded interpreters using a modified high-res
olution CT technique (HRCT) and FOB was designed to evaluate 57 consec
utive patients admitted to Bellevue Hospital with hemoptysis. Etiologi
es included bronchiectasis (25 percent), tuberculosis (16 percent),lun
g cancer (12 percent), aspergilloma (12 percent), and bronchitis (5 pe
rcent): in an additional 5 percent of cases, hemoptysis proved to be d
ue miscellaneous causes, while in 19 percent hemoptysis proved to be c
ryptogenic. Patients with lung cancer all were at least 50 years old,
smoked an average of 78 pack-years, and had less severe hemoptysis but
of longer duration. All had conditions diagnosed both by HRCT and FOB
. High-resolution CT proved of particular value in diagnosing bronchie
ctasis and aspergillomas, while FOB was diagnostic of bronchitis and m
ucosal lesions such as Kaposi's sarcoma. Fiberoptic bronchoscopy local
ized bleeding in only 51 percent of cases. The high sensitivity of CT
in identifying both the intraluminal and extraluminal extent of centra
l lung cancers in conjunction with its value in diagnosing bronchiecta
sis suggest that CT should be obtained prior to bronchoscopy in all pa
tients presenting with hemoptysis.