MICROWAVE ENHANCED KNOEVENAGEL CONDENSATION OF ETHYL CYANOACETATE WITH ALDEHYDES

Authors
KIM SY KWON PS KWON TW CHUNG SK CHANG YT
Citation
Sy. Kim et al., MICROWAVE ENHANCED KNOEVENAGEL CONDENSATION OF ETHYL CYANOACETATE WITH ALDEHYDES, Synthetic communications, 27(4), 1997, pp. 533-541
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
27
Issue
4
Year of publication
1997
Pages
533 - 541
Database
ISI
SICI code
0039-7911(1997)27:4<533:MEKCOE>2.0.ZU;2-J
Abstract
The reaction rate of Knoevenagel condensation can be dramatically enha nced by irradiating the reaction mixture containing ethyl cyanoacetate , an aldehyde, P2O5, piperidine, and chlorobenzene with a commercial m icrowave oven. A number of Knoevenagel condensation products were prep ared in good yields in very short reaction times (2-15min) under the m icrowave irradiation.