A CONVENIENT ONE-POT PROCEDURE FOR N-METHYLATION OF AROMATIC-AMINES USING TRIMETHYL ORTHOFORMATE

Authors
PADMANABHAN S REDDY NL DURANT GJ
Citation
S. Padmanabhan et al., A CONVENIENT ONE-POT PROCEDURE FOR N-METHYLATION OF AROMATIC-AMINES USING TRIMETHYL ORTHOFORMATE, Synthetic communications, 27(4), 1997, pp. 691-699
Citations number
36
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
27
Issue
4
Year of publication
1997
Pages
691 - 699
Database
ISI
SICI code
0039-7911(1997)27:4<691:ACOPFN>2.0.ZU;2-X
Abstract
Aromatic amines react with trimethyl orthoformate in the presence of c oncentrated sulfuric acid followed by acid hydrolysis to afford mono m ethylated amines in moderate to good yields.