SYNTHESIS OF C-14-LABELED BROMOCRESOL GREEN AND METACRESOL PURPLE

Citation
P. Thourel et al., SYNTHESIS OF C-14-LABELED BROMOCRESOL GREEN AND METACRESOL PURPLE, Journal of labelled compounds & radiopharmaceuticals, 34(3), 1994, pp. 275-279
Citations number
13
Categorie Soggetti
Chemistry Analytical","Pharmacology & Pharmacy
ISSN journal
03624803
Volume
34
Issue
3
Year of publication
1994
Pages
275 - 279
Database
ISI
SICI code
0362-4803(1994)34:3<275:SOCBGA>2.0.ZU;2-X
Abstract
[methyl-C-14]-Bromocresol green 1 was synthesized from [C-14] - methyl iodide in four steps via 3-[methyl-C-14]-methylanisole 3, [methyl-C-1 4]-metacresol 4 and [methyl-C-14]-metacresol purple 6. The overall yie ld of 1 from [C-14] methyl iodide was 5.3 % and the specific activity 112 mCi/mmol.