MERKEL CELL TUMOR OF THE EYELID AND THE CYTOLOGIC ASPECT IN FINE-NEEDLE ASPIRATES - REPORT OF A CASE

We describe one case of Merkel cell tumor (MCT) of the eyelid diagnose d by fine-needle aspiration (FNA). The main cytologic features were: i solated cells, loose cohesive sheets, and rosette-like structures in a hematic background The cells were round to ovoid and very uniform. Ch romatin was finely granular and frequent mitotic figures were observed . Under close scrutiny small faintly stained juxtanuclear ''caps '' we re seen. A strong dot-like positivity for CK22 and NFP was observed in the position corresponding to the ''caps. '' NSE positivity was diffu se, although a weak dot-like positivity was seen in some cells. S-100 was negative. Both the cytologic features and the immunocytologic prof ile of Merkel cell tumor are very characteristic. FNA enables an early and confident diagnosis of th is aggressive tumor and an early planni ng of surgery. (C) 1994 Wiley-Liss, Inc.