Jm. Cooney et al., EFFECT OF SOLID SUBSTRATE, LIQUID SUPPLEMENT, AND HARVEST TIME ON 6-N-PENTYL-2H-PYRAN-2-ONE (6PAP) PRODUCTION BY TRICHODERMA SPP, Journal of agricultural and food chemistry, 45(2), 1997, pp. 531-534
Selected strains of Trichoderma spp. were grown on 10 different solid
media substrates and analyzed for the production of 6-n-pentyl-2H-pyra
n-2-one (6PAP). Using the highest yielding medium from this study, gro
und corn plus a liquid supplement, 15 Trichoderma isolates were screen
ed, and this led to the identification of two high yielding strains. B
y selection of solid media, liquid supplement, and harvest time, the y
ield of 6PAP was improved from ca. 200 up to about 1000 mg/kg. These r
esults will provide an indication for future production studies leadin
g to the development of a bulk-scale fermentation process.