N. Williams et al., INCIDENCE AND MANAGEMENT OF CATHETER-RELATED SEPSIS IN PATIENTS RECEIVING HOME PARENTERAL-NUTRITION, British Journal of Surgery, 81(3), 1994, pp. 392-394
Fifty patients, comprising 24 male and 26 female of median four cases)
and ten of exit-site sepsis (all managed by age 43 (range 15-67) year
s, received a total of 2620 patient-months of home parenteral nutritio
n (median 48 (range 2-130) months). There were 13 episodes of bacteria
l catheter sepsis (of which the catheter was successfully salvaged by
an antibiotic-fibrinolytic 'lock' technique in four cases) and ten of
exit-site sepsis (all managed by elective catheter replacement), repre
senting an incidence of 1 septic complication per 113 patient-months o
f parenteral nutrition. This low incidence of catheter-related sepsis
was achieved by strict adherence to established protocols of catheter
management.