The cuniculatum carcinoma is a rare type of epidermoid carcinoma. We r
eport 6 cases with different localizations (<<oral cavity and larynx>>
, vulva, lower limb) treated over a 23-year period Diagnosis is partic
ularly difficult and requires careful clinical examination completed b
y deep surgical biopsy for histology. The aetiology of the tumour is n
ot well defined It presents as a slow growing wart with local malignan
cy and chronic supperation. Extention to lymph nodes is rare. Histolog
ically there is proliferative deep malpighian infiltration with an asp
ect of normal cell maturation. Galeries are hollowed out giving the as
pect of a rabbit burrow (cuniculatum). Surgery is the only treatment,
generally without lymph node curage. Radiotherapy is contraindicated d
ue to anaplasic transformation.