PREDICTION OF REPOPULATION RATES AND RADIOSENSITIVITY IN HUMAN TUMORS

An accurate prediction of response to radiotherapy would allow treatme nts to be modified for those individuals where a relatively poor respo nse is expected with conventional treatment. Present assays receiving most attention are those for repopulation, radiosensitivity and hypoxi a. This paper discusses our experience with the first two, together wi th relevant data from other groups. Attention is focussed particularly on correlations with outcome in clinical trials, and the accuracy of present assay methods.