Jr. Nethercott et Dl. Holness, DISEASE OUTCOME IN WORKERS WITH OCCUPATIONAL SKIN-DISEASE, Journal of the American Academy of Dermatology, 30(4), 1994, pp. 569-574
Background: Occupational contact dermatitis (OCD) contributes signific
antly to the burden of occupational disease, but there is little known
about prognostic factors. Objective: The study was designed to determ
ine the health status of workers with OCD at least 2 years after diagn
osis and to identify risk factors related to prognosis. Methods: A que
stionnaire study was conducted of workers with a diagnosis of work-rel
ated skin disease. Results: Of the 201 workers with OCD, 76% noted imp
rovement and 40% reported that they were currently free of any eruptio
n. Approximately one third noted that their skin disease interfered wi
th household, work, or recreational activities. The key prognostic fac
tor appeared to be sex because women reported a better outcome. Diagno
sis and atopic status tended to be related to some outcomes, whereas a
ge was not. Conclusion: Examination of other possible factors, some of
which may be associated with sex, that might affect outcome should be
undertaken to gain a better understanding of possible management stra
tegies. A retrospective study has methodologic limitations and a prosp
ective intervention trial should yield more information.