STEREOSELECTIVE SYNTHESIS OF NOVEL ANALOGS OF 2'DEOXYNUCLEOSIDES AND 2',3'-DIDEOXYNUCLEOSIDES WITH POTENTIAL ANTIVIRAL ACTIVITY

Citation
Do. Cicero et al., STEREOSELECTIVE SYNTHESIS OF NOVEL ANALOGS OF 2'DEOXYNUCLEOSIDES AND 2',3'-DIDEOXYNUCLEOSIDES WITH POTENTIAL ANTIVIRAL ACTIVITY, Bioorganic & medicinal chemistry letters, 4(7), 1994, pp. 861-866
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
ISSN journal
0960894X
Volume
4
Issue
7
Year of publication
1994
Pages
861 - 866
Database
ISI
SICI code
0960-894X(1994)4:7<861:SSONAO>2.0.ZU;2-F
Abstract
The stereoselective synthesis of new 2'-deoxy- and 2',3'-dideoxy-2'-C- alkylnucleosides with potential antiviral activity is presented. The c ompounds here described were tested for their antiproliferative proper ty against human tumor cell lines and none showed any significant anti tumor activity.