THE LIPASE-CATALYZED SYNTHESIS OF CARBAMOYLOXYETHYL METHACRYLATE

Authors
DERANGO R WANG YF DOWBENKO R CHIANG LC
Citation
R. Derango et al., THE LIPASE-CATALYZED SYNTHESIS OF CARBAMOYLOXYETHYL METHACRYLATE, Biotechnology letters, 16(3), 1994, pp. 241-246
Citations number
6
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
16
Issue
3
Year of publication
1994
Pages
241 - 246
Database
ISI
SICI code
0141-5492(1994)16:3<241:TLSOCM>2.0.ZU;2-V
Abstract
The first example of an enzymatic synthesis of 2-carbamoyloxyethyl met hacrylate by a lipase-catalyzed transesterification of 2-hydroxyethylc arbamate with vinyl methacrylate in organic solvent is reported. Using the lipase PS-30 from the Pseudomonas species under optimal condition s, a temperature of 50 degrees C and a solvent mixture (3:1) toluene/T HF, carbamoyloxyethyl methacrylate is produced at a quantitative yield in 72 hours.