ANTIBODY-RESPONSE TO PLASMODIUM-VIVAX ANTIGENS IN HUMAN MALARIA

Authors
SANCHEZ MR RAMIREZ JA RODRIGUEZ MH OREILLY F LARRALDE C ORTIZORTIZ L
Citation
Mr. Sanchez et al., ANTIBODY-RESPONSE TO PLASMODIUM-VIVAX ANTIGENS IN HUMAN MALARIA, The American journal of tropical medicine and hygiene, 50(3), 1994, pp. 329-338
Citations number
30
Categorie Soggetti
Public, Environmental & Occupation Heath","Tropical Medicine
Journal title
The American journal of tropical medicine and hygiene → ACNP
ISSN journal
00029637
Volume
50
Issue
3
Year of publication
1994
Pages
329 - 338
Database
ISI
SICI code
0002-9637(1994)50:3<329:ATPAIH>2.0.ZU;2-0
Abstract
The present study investigated the serum antibody response to parasite antigens involved in human Plasmodium vivax malaria. Analysis was per formed by protein immunoblotting of a pool of P. vivax preparations ob tained from blood of patients from Tapachula, Chiapas (southeastern Me xico), and sera from local malarious patients. Patient sera recognized 19 P. vivax antigens with molecular sizes between 17 and 170 kD. The most frequently recognized antigens were proteins of 19, 31, 43, 72, 9 3, and 97 kD. These proteins could be useful in diagnostic methods and possibly relevant in vaccine design.