A neonate presented with cloverleaf skull anomaly and severe proptosis
requiring urgent cranioplasty to attain eyelid closure. Despite this,
she experienced exposure keratitis and corneal perforations. A ventri
culoperitoneal shunt was performed subsequently to relieve hydrocephal
us, but respiratory problems eventually led to her death at 6 months.
This case highlights the complexity of the problems encountered in the
cloverleaf skull anomaly, and a brief review discussing its managemen
t is included. Despite improvements in treatment of this condition, th
e overall prognosis remains poor.